Rat liver intoxication with CCl4: biochemistry, histology, and mass spectrometry
نویسندگان
چکیده
منابع مشابه
Electrospray and tandem mass spectrometry in biochemistry.
Over the last 20 years, biological MS has changed out of all recognition. This is primarily due to the development in the 1980s of 'soft ionization' methods that permit the ionization and vaporization of large, polar, and thermally labile biomolecules. These developments in ionization mode have driven the design and manufacture of smaller and cheaper mass analysers, making the mass spectrometer...
متن کاملEffect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C.
BACKGROUND Steatosis occurs in more than 50% of patients with chronic hepatitis C and is associated with increased hepatic fibrosis. In many of these patients the pathogenesis of steatosis appears to be the same as for patients with non-alcoholic fatty liver disease-that is, related to visceral adiposity and obesity. METHODS The effect of a three month weight reduction programme on liver bioc...
متن کاملPropofol Attenuates Toxic Oxidative Stress by CCl4 in Liver Mitochondria and Blood in Rat
Anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet CCl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). Group I (control), while Group II was given CCl4 (3 mL /Kg/day, IP). Animals of Groups III received only propofol (10 mg/Kg/day, IP). Group IV was given propofol+ CCl4. Group V was admin...
متن کاملPropofol Attenuates Toxic Oxidative Stress by CCl4 in Liver Mitochondria and Blood in Rat
Anti-oxidant effects of propofol (2, 6-diisopropylphenol) were evaluated agains carbon tetrachloridet CCl4 -induced oxidative stress in rat liver. 30 male rats were equally divided in to 6 groups (5 rats each). Group I (control), while Group II was given CCl4 (3 mL /Kg/day, IP). Animals of Groups III received only propofol (10 mg/Kg/day, IP). Group IV was given propofol+ CCl4. Group V was admin...
متن کاملLIVER AND BILIARY DISEASE Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C
Background: Steatosis occurs in more than 50% of patients with chronic hepatitis C and is associated with increased hepatic fibrosis. In many of these patients the pathogenesis of steatosis appears to be the same as for patients with non-alcoholic fatty liver disease—that is, related to visceral adiposity and obesity. Methods: The effect of a three month weight reduction programme on liver bioc...
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ژورنال
عنوان ژورنال: General physiology and biophysics
سال: 2018
ISSN: 1338-4325
DOI: 10.4149/gpb_2018011